Ключевое слово: «hydrolysis.»
RESEARCH IN THE FIELD OF SYNTHESIS OF METHYL ESTER 6 CARBOXYFASCAPLYSIN // Научно-методический электронный журнал «Концепт». – 2026. – . – URL: http://e-koncept.ru/2026/0.htm
The alkaloid fascaplysin has a wide range of antitumor and antibacterial activity. One important area of research is the synthesis of new fascaplysin derivatives. In this study, we demonstrate a new approach to the targeted introduction of a carboxyl group into the fascaplysin structure. The developed method is based on the preparation of a β-carboline derivative from the methyl ester of the readily available amino acid tryptophan, followed by quaternization to form the methyl ester of 6-carboxyfascaplysin.
