Changes in the formation of a new technological foundation are based on the introduction of innovative scientific achievements in all spheres of society, therefore, there is an acute issue of the availability of scientific and technical potential and high-tech production, the solution of which largely depends on the quality level of professional personnel and their competitiveness. The article describes the essential content of the system of scientific organization of labor in preparing participants for the WorldSkills championship and gives the analysis of domestic and foreign scientific literature, revealing the principles of the scientific organization of labor to improve competitiveness in professional activities. The purpose of the study is to theoretically substantiate the use of the principles of scientific organization of labor to increase competitiveness in preparation for the WorldSkills championship. The methodological basis of the study is the idea of technological, competence, systemic approaches, general scientific methods of comparative analysis (historical retrospective), synthesis and generalization. The theoretical significance of the article is as follows: the authors reveal the content of the labor scientific organization concept to increase competitiveness in preparation for the WorldSkills championship as a process of organizing professional labor aimed at increasing its productivity; present a retrospective of the views of Russian and foreign scientists on the essence of the concept of labor scientific organization, which includes elements and tasks of labor organization, revealing the importance of the process under study for the system of effective training of competitive personnel; examine the systems of labor motivation in different periods of our country development; substantiate the principles of scientific organization of labor to increase competitiveness in preparation for the WorldSkills championship. The practical significance of the article lies in the fact that the conclusions and provisions contained in it reveal the principles of the scientific organization of labor to increase competitiveness in preparation for the WorldSkills championship, which is confirmed by the results of the study. The authors note that the main emphasis should be placed on early vocational guidance, motivation and stimulation of young people and students, increasing the prestige of blue-collar occupations with the help of forms and methods of vocational training, which are based on the principles of the scientific organization of labor.